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  • Prudent J, McBride HM. The mitochondria-endoplasmic reticulum contact sites: a signalling platform for cell death. Curr Opin Cell Biol. 2017 Apr 6;47:52-63. doi: 10.1016/j.ceb.2017.03.007. [Epub ahead of print] (CCSRI-Innovation to Impact).

  • Doiron K, Goyon V, Coyaud E, Rajapakse S, Raught B, McBride HM. The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity. Sci Rep. 2017 Dec;7(1):107. doi: 10.1038/s41598-017-00151-6. (International Development Research Center (IDRC) and CIHR Project Grant).

  • Sugiura A, Mattie S, Prudent J, McBride HM. Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes. Nature. 2017 Feb 9;542(7640):251-254. doi: 10.1038/nature21375. (CIHR#133549).

*Article subject of commentary in Nature. 2017 Feb 9;542(7640):174-175. doi: 10.1038/nature21496, Cell Death Differ. 2017 Apr 14. doi: 10.1038/cdd.2017.23, and Curr Biol. 2017 Apr 3;27(7):R271-R274. doi: 10.1016/j.cub.2017.02.052.

  • McBride HM, Frost A. Cell biology: Double agents for mitochondrial division. Nature. 2016 Dec 1;540(7631):43-44 (News and Views commentary).

  • McLelland GL, Lee SA, McBride HM, Fon EA. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016 Aug 1;214(3):275-91.  (CIHR#133549)

  • Cadete VJ, Deschênes S, Cuillerier A, Brisebois F, Sugiura A, Vincent A, Turnbull D, Picard M, McBride HM, Burelle Y.J Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system. Physiol. 2016 Sep 15;594(18):5343-62. (CIHR#133549)
  • Matheoud D, Sugiura A, Bellemare-Pelletier A, Laplante A, Rondeau C, Chemali M, Fazel A, Bergeron JJ, Trudeau LE, Burelle Y, Gagnon E, McBride HM*, Desjardins M*.Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation. Cell. 2016 Jul 14;166(2):314-27. *co-corresponding authors. (CIHR#133549)

*Article subject of Commentary in Cell Metab. 2016 Jul 12;24(1):11-2, in Cell Reports 2016 Nov;26(11):1180-1181, and in  Trends Immunology 2016 Nov;37(11):719-721.

  • Prudent J, McBride HM. Mitochondrial dynamics: ER actin tightens the Drp1 Noose. Current Biology 2016 Mar 7;26(5):R207-9. (Dispatch)

  • Prudent J, Zunino R, Sugiura A, Mattie S, Shore GC, McBride HM. MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death. Mol Cell. 2015 Sep 17;59(6):941-55. (CIHR#68833 and CCSRI)

  • McBride HM. Open questions: seeking a holistic approach for mitochondrial research. BMC Biol. 2015 Feb 5;13(1):8.

  • Sugiura A, McLelland GL, Fon EA, McBride HM. A new pathway for mitochondrial quality control: mitochondrial-derived vesicles. EMBO J. 2014 Oct 1;33(19):2142-2156. (HSFO 5769)

  • McLelland GL, Soubannier V, Chen CX, McBride HM*, Fon EA*. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J. 2014 Feb 18;33(4):282-95. (*co-corresponding author) HSFO 5769 and BRP

*Article highlighted as “Editor’s Choice” in Science vol 343, issue 6171, page 577, 2014

*Article subject of “Have you seen” commentary in EMBO J vol. 33 no. 4 277-279, 2014

*Article chosen as “Research Highlight” in Nature Rev. Mol. Cell. Biol. 15,150–151, 2014

*Article selected for F1000 “recommended”.

  • Mohanty, A., and McBride, H.M. Emerging roles of mitochondria in the evolution, biogenesis and function of peroxisomes. Frontiers in Neuroscience. 2013 Sep 26;4:268. eCollection 2013.CIHR 68833
  • Soubannier V, Rippstein P, Kaufman BA, Shoubridge EA, McBride HM. Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo. PLoS One. 2012;7(12):e52830. HSFO 5769
  • Shutt, T.*, Geoffrion, M., Milne, R., and McBride, H.M. The intracellular redox state is a core determinant of mitochondrial fusion. EMBO Rep. 2012 Oct;13(10):909-15. CIHR 43935

*Article subject of commentary in EMBO Rep. 2012 Oct;13(10):870-1.

  • Shutt TE, McBride HM. Staying cool in difficult times: Mitochondrial dynamics, quality control and the stress response. Biochim Biophys Acta. 2013 Feb;1833(2):417-24. CIHR 43935
  • Soubannier V, McLelland GL, Zunino R, Braschi E, Rippstein P, Fon EA, McBride HM. A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Curr Biol. 2012 Jan 24;22(2):135-41. HSFO 5769 and Neuro BRP

*Article highlighted in Nature Reviews Molecular Cell Biology 13, 63 (February 2012).

*Article selected for Faculty of 1000 “recommended”

  • Braschi, E., Goyon, V., Zunino, R., Mohanty, A., Xu, L. and McBride, H.M. Vps35 mediates vesicle transport between the mitochondria and peroxisomes. Current Biology, 20(14):1310-5, 2010. HSFO 5769.

*Article selected for Faculty of 1000 “recommended”.

  • Schauss, A.C., Huang, H., Choi, S-Y, Xu, L., Bilodeau, P., Zunino, R., Rippstein, P., Frohman, M.A., and McBride, H.M. A novel cell-free mitochondrial fusion assay demonstrates regulation through intracellular signaling cascades. BMC Biology Jul 26;8:100, 2010. CIHR 43935.

*Article subject of a Commentary in BMC Biol. 2010 Jul 26;8:99.

  • Braschi, E., Zunino, R., and McBride, H.M. MAPL is a novel mitochondrial SUMO E3 ligase that regulates mitochondrial fission. EMBO Reports, 10(7):748-54, 2009. CIHR 68833.

*Article highlighted with Commentary in EMBO Reports.

*Article selected for Faculty of 1000 “must read”.

  • Andrade-Navarro, M.A., Sanchez-Pulido, L., and McBride, H.M. Mitochondrial vesicles: an ancient process providing new links to peroxisomes. Current Opinion in Cell Biology; 21(4):560-7, 2009
  • Zunino, R., Braschi, E., Xu, L., and McBride, H.M. Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1 dependent fission during mitosis. Journal of Biological Chem. 284(26):17783-95, 2009. CIHR 68833
  • McBride, H.M. Parkin mitochondria in the autophagosome. Journal of Cell Biol. 183, 757-759, 2008. Invited commentary
  • Soubannier, V. and McBride H.M. Positioning mitochondrial plasticity within cellular signaling cascades. Biochem. Biophys. Acta (Molecular Cell Biology), 1793(1):154-70, 2009 review
  • Neuspiel, M., Schauss, A.C., Braschi, E., Zunino, R., Rippstein, P., Rachubinski, R.A., Andrade-Navarro, M.A., and McBride, H.M. Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Current Biology. 18(2), 102-108, 2008. HSFO 5769

*Article chosen as a Research Highlight in Nature Reviews Molecular Cell Biology 9, 186-187 (March 2008)

*Article selected for Faculty of 1000 “must read”

*Article subject to a commentary in Trends in Cell Biology 18(6):253-6, 2008

  • Wasiak, S., Zunino, R. and McBride, H.M. Bax/Bak promote SUMOylation of DRP1 and its stable association with mitochondria during apoptotic cell death. Journal of Cell Biology. 177: 439-450, 2007 CIHR 68833

*Article selected for Faculty of 1000 “recommended”

  • Zunino, R., Rippstein, P., Andrade-Navarro, M., and McBride, H.M. The SUMO protease SenP5 is required to maintain mitochondrial morphology and function. Journal of Cell Science, 120(7):1178-1188, 2007 CIHR 68833

*Article highlighted “In this Issue” title: SUMO wrestling in mitochondria. Journal of Cell Science, 120: e703, 2007

  • Schauss, A,C. and McBride, H.M. Mitochondrial Fission: A Non-Nuclear Role for Num1p Current Biology Vol 17, R467-R470, 2007 (Dispatch). CIHR 68833
  • Jahani-Asl, A., Cheung, E.C.C., Neuspiel, M., Xu, W., MacLaurin, J.G., Fortin, A., Park, D.S., McBride, H.M.*, Slack, R.S. Dynamic fusion of mitochondria protects neurons against oxidative stress and exitotoxicity. J.Biol Chem. 282(33):23788-98, 2007. *co-corresponding author. CIHR 43935
  • Jeyaraju, D., Xu, L., Letellier, M.C, Davidovic, L., Berg, E.A., McBride, H.M.*, and Pellegrini, L*. Phosphorylation of the vertibrate rhomboid protease PARL regulates mitochondrial morphology. PNAS (Track II),103(49) 18562-18567, 2006 *co-corresponding author. (Jayaraju and Xu co-first author) CIHR 43935
  • McBride, H.M., Neuspiel, M., Wasiak, S. Mitochondria: More than just a powerhouse. Current Biology. 16(14):R551-R560, 2006
  • Neuspiel, M., Zunino, R., Gangaraju, S., Rippstein, P. and McBride H.M. Activated Mfn2 has signaling capabilities, represses Bax activation and protects against permeability transition. J. Biol. Chem. 280(26):25060-25070, 2005. CIHR 43935
  • Germain, M., Mathai, J.P., McBride, H.M.*, and Shore, G.C*. Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae and mobilization of cytochrome c during apoptosis. EMBO J. 24(8):1546-56, 2005 *co-corresponding author. CIHR 43935
  • Harder, Z., Zunino, R., and McBride, H.M. SUMO-1 participates with DRP1 in mitochondrial fission events. Current Biology, 14: 340-345, 2004. CIHR 43935